When repeated cannabis use results in diminished effects, this is known as marijuana tolerance. It also implies that greater dosages are required to produce the same therapeutic effects. Changes in the endocannabinoid system (ECS), which controls important processes like mood, pain, and sleep, are the cause of this. If you’re noticing these tolerance effects and are looking for alternative treatment options, you can now get MMJ card online to explore medical cannabis solutions tailored to your needs.
The effects of the psychoactive substance THC are caused by interactions with CB1 receptors in the ECS. These receptors lose their sensitivity or quantity with repeated use. We call this downregulation of receptors. Tolerance results as a result of the body becoming less sensitive to THC.
High-THC products, frequent use, and inhalation techniques like smoking or vaping accelerate the development of tolerance. Genetics, metabolism, and an individual’s ECS sensitivity all play a role.
By taking tolerance breaks and quitting cannabis use, you can reverse your tolerance. It enables the resetting and sensitivity restoration of CB1 receptors.
Tolerance vs. Dependence: Understanding the Difference
- Tolerance: Needing more of a substance to have the same effect is referred to as tolerance.
- Dependency: Describes the experience of withdrawal symptoms upon cutting back or quitting a substance.
Tolerance can be developed without dependence, and vice versa.
Key Factors Affecting Tolerance and Dependence on Medical Marijuana
Whether a patient develops dependence or tolerance depends on a number of factors, such as:
- Compared to infrequent use, daily use raises the risk of tolerance or dependence. These problems are more likely to be exacerbated by products with high THC content.
- In addition to not producing tolerance or dependence, CBD may even mitigate some of the negative effects of THC.
- Compared to edibles or tinctures, inhalation (smoking or vaping) produces effects more quickly and intensely, which may hasten the development of tolerance.
How to Reset Your Cannabis Tolerance
Here are some methods for managing or resetting cannabis tolerance while preserving symptom relief.
Take a Tolerance Break
A T-break, also known as a tolerance break, is a brief cessation of cannabis use that enables the body to re-establish its sensitivity to THC. Patients may be able to recover the intended therapeutic effects as a result.
Depending on your objectives, tolerance breaks can last anywhere from one to thirty-five days. Because the body breaks down cannabinoids quickly, even a brief 24- to 48-hour break can reduce tolerance.
The majority of THC traces are eliminated by the body during a longer break (such as 30 days), which restores baseline sensitivity. In addition to increasing the effects of THC, T-breaks can reduce costs.
See your physician if you are a medical cannabis patient thinking about getting a T-break.
Gradually Reduce Cannabis Use
For medical marijuana patients, gradual adjustments can lower tolerance while maintaining symptom control. If your current dose manages your symptoms (e.g., 20 mg THC and 10 mg CBD per day), avoid increasing it. Staying consistent prevents rapid tolerance buildup.
Use minimal THC doses and gradually increase until symptoms improve. This helps maintain efficacy while reducing the likelihood of developing tolerance.
Consider alternating strains or products with different cannabinoid and terpene profiles to prevent the body from becoming dependent on one formulation. Consult your doctor for these adjustments.
Balancing Cannabis
Finding your “sweet spot” is crucial when using cannabis as medicine. Although excessive use of cannabis can result in tolerance, it should elevate mood and lessen symptoms. For this reason, for safe and efficient use, you should start with a low dose and increase it gradually.
Utilizing products that contain a range of terpenes and cannabinoids can also improve therapeutic effects and avoid side effects.
By adhering to these recommendations, you can prevent negative side effects and guarantee that cannabis will reach its maximum potential. Cannabis will yield consistent and significant benefits if you treat it like any other medication.
Do you want to include cannabis in your medical regimen? Visit Online Medical Card to apply for a medical marijuana card. And if you’re interested in taking it a step further, check out our resources on obtaining a CA cannabis grower license.
For any inquiries concerning our cannabis cards or products, get in touch with us.
